CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in medical and biomedical sciences.
Edited by: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP)
Clinics
ISSN: 1807-5932
e-ISSN: 1980-5322

Clinics is a gold open access electronic international journal that publishes peer-reviewed research in continuous flow of interest to clinicians and researchers in medical and biomedical sciences based on its originality, importance, conclusions and interest to readers. CLINICS also publishes Comments and Editorials. The journal is committed to the principles of ethics, respect for the individual, humanization, honesty, pioneering spirit and excellence.Clinics is the Official Scientific journal of Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP).

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Indexed in:

Clarivate/ISI: Web of Sciences, SCOPUS, PubMed Central (PMC), SciELO Brasil, SciELO Public Health, Redalyc, EMBASE, Nutrition Abstracts & Reviews, POPLINE, Tropical Diseases Bulletin, LILACS

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Impact factor

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years.

© Clarivate Analytics, Journal Citation Reports 2022

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Impact factor 2022
2.7
Citescore

CiteScore measures average citations received per document published.

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Citescore 2022
3.5
SJR

SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact.

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SJR 2022
0.501
SNIP

SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field.

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SNIP 2022
0.726
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Last published articles
Review articles
Comparison of gefitinib plus chemotherapy versus gefitinib alone for advanced non‑small‑cell lung cancer: A meta analysis
Min Yi, Ting He, Kaijin Wang, Yonggang Wei
Highlights

  • This meta-analysis shows that gefitinib plus chemotherapy showed significantly better efficacy in improving objective response rate, disease control rate, progression-free survival, and OS as compared with gefitinib alone.

  • Similar efficacy of gefitinib plus chemotherapy is found in the sub-population with positive EGFR mutation.

  • The toxicity of gefitinib plus chemotherapy is also increased but within clinical management.

Open access
Correspondence
Neurophysics: Understanding brain activity with modeling complex systems mathematics
Fulvio A. Scorza, Ana C. Fiorini, Antônio M. Rodrigues, Carla A. Scorza, Gabriel D. Vilallonga, Marcelo A. Moret, Tarcísio M. Rocha Filho, Josef Finsterer, Antônio-Carlos G. de Almeida
Open access
Editorial
COVID-19 in children and adolescents with neuroimmunological disorders
Ingrid Lacerda Pessoa, Renata Barbosa Paolilo, José Albino da Paz
Open access
Original articles
Dysarthria in hereditary spastic paraplegia type 4
Lais Alves Jacinto-Scudeiro, Rui Rothe-Neves, Vanessa Brzoskowski dos Santos, Gustavo Dariva Machado, Daniela Burguêz, Marina Martins Pereira Padovani, Annelise Ayres, Rafaela Soares Rech, ... Maira Rozenfeld Olchik
Highlights

  • • Prevalence of dysarthria in SPG4 is greater than previously considered.

  • • The dysarthria in SPG4 is mild or moderate.

  • • The subsystems of speech more affected are articulatory and phonation.

Open access
Changes in clinical and CT manifestations related to liver abscesses in patients with vs. without basic diabetes mellitus before and after CT-guided interventional therapy: An observational study
Yuxiang Chen, Xunfu Lai, Yuping Zhu, Mengting Wang, Yulin He
Highlights

  • Liver abscess patients with diabetes mellitus have featured presentations.

  • Liver abscess patients with diabetes mellitus have featured changes after therapy.

  • Liver abscess patients with diabetes mellitus cannot have a better therapeutic effect.

Open access
LncRNA ZFAS1 contributes to osteosarcoma progression via miR-520b and miR-520e-mediated inhibition of RHOC signaling
Xiaofeng Liu, Mingyang Wang, Liwen Zhang, Lei Huang
Highlights

  • Lnc-ZFAS1 is highly expressed in osteosarcoma.

  • Lnc-ZFAS1 could promote cell proliferation, migration, invasion and EMT in vitro.

  • Lnc-ZFAS1 acted sponger of miR-520b and miR-520e to promote RHOC.

Open access
Intra-abdominal desmoid tumors in familial adenomatous polyposis: How much do clinical and surgical variables interfere with their development?
Fábio Guilherme Campos, Carlos Augusto Real Martinez, Leonardo Alfonso Bustamante-Lopez, Roberta Laís da Silva Mendonça, Danillo Toshio Kanno
Highlights

  • Desmoid Tumors in Familial Adenomatous Polyposis are a huge problem in these patients, the ability to prevent desmoid development is limited.

  • Some clinical and surgical variables were identified as unfavorable and associated with a greater risk.

  • This variable may be useful during the decision-making process.

Open access
Review articles
Comparison of gefitinib plus chemotherapy versus gefitinib alone for advanced non‑small‑cell lung cancer: A meta analysis
Min Yi, Ting He, Kaijin Wang, Yonggang Wei
Highlights

  • This meta-analysis shows that gefitinib plus chemotherapy showed significantly better efficacy in improving objective response rate, disease control rate, progression-free survival, and OS as compared with gefitinib alone.

  • Similar efficacy of gefitinib plus chemotherapy is found in the sub-population with positive EGFR mutation.

  • The toxicity of gefitinib plus chemotherapy is also increased but within clinical management.

Open access
Endoscopic Biliary Darinage (EBD) versus Percutaneous Transhepatic Biliary Drainage (PTBD) for biliary drainage in patients with Perihilar Cholangiocarcinoma (PCCA): A systematic review and meta-analysis
Caroline Flaksbaum Moll, Diogo Turiani Hourneaux de Moura, Igor Braga Ribeiro, Igor Mendoça Proença, Epifanio Silvino do Monte Junior, Sergio A. Sánchez-Luna, Maria Fernanda Shinin Merchán, Josselyn Mariana Vera Intriago, ... Eduardo Guimarães Hourneaux de Moura
Highlights

  • There is no consensus about which method is preferred for biliary drainage for Perihilar Cholangiocarcinoma (PCCA).

  • Endoscopic retrograde cholangiopancreatography (EBD) or Percutaneous Transhepatic Biliary Drainage (PTBD) are options of choice.

  • PTBD is superior to EBD regarding crossover rate, overall post-drainage complications, and post-drainage pancreatitis.

  • EBD is superior to PTBD when it comes to hospital length of stay.

  • For the palliation of PCCA, PTBD is superior to EBD in terms of clinical success and post-drainage cholangitis.

Open access
From H1N1 to COVID-19: What we have seen in children with hemoglobinopathies
Claudia de Melo Oliveira, Victor Jablonski Soares, Ciliana Rechenmacher, Liane Esteves Daudt, Mariana Bohns Michalowski
Clinics. 2022;77C:100004
Highlights

  • Children with hemoglobinopathies have less severe conditions with Coronavirus 2019 Disease (COVID-19) compared to adults, which is similar to that observed in the general population

  • In the H1N1 pandemic, patients with hemoglobinopathies behaved as the group most susceptible to complications, with increased morbidity and mortality

Full text access
Inhibition of Toll-like Receptor-4 expression for amelioration of myocardial injury in diabetes: A meta-analysis
Jinxin Yuan, Xingwen Yin, Hua Jiang
Clinics. 2022;77C:100137
Highlights

  • A meta-analysis was applied to understand the relationship between inhibition of Toll-like Receptor 4 and diabetic myocardial injury.

  • Inhibition of Toll-like Receptor 4 expression levels can improve the degree of cardiac impairment.

  • Toll-like Receptor 4 may become a new target for the treatment of diabetic cardiomyopathy.

Full text access
Comments
Care coordination in pediatrics: Experience of the outpatient clinic for Children with Special Health Care Needs (CSHCN)
Ana Paula Scoleze Ferrer, Daleth Rodrigues Scaramuzzi, Maria Lúcia M. Bourroul, Sandra M.C. Zuccolotto, Sandra J.F.E. Grisi
Clinics. 2022;77C:100049
Full text access
The implication of cardio-oncology on Parkinson's disease: answers begin to emerge
Fulvio A. Scorza, Antonio-Carlos G. de Almeida, Josef Finsterer, Ludhmila A. Hajjar
Clinics. 2022;77C:100085
Full text access
Sudden unexpected death in epilepsy and abnormal glucose metabolism in the rat insular cortex: A brain within the heart
Fulvio A. Scorza, Antonio-Carlos G. de Almeida, Carla A. Scorza, Josef Finsterer
Clinics. 2022;77C:100059
Full text access
Erratums
Erratum to Persistent symptoms and decreased health-related quality of life after symptomatic pediatric COVID-19: A prospective study in a Latin American tertiary hospital” [Clinics. 2021;76:e3511]
Thais T. Fink, Heloisa H.S. Marques, Bruno Gualano, Livia Lindoso, Vera Bain, Camilla Astley, Fernanda Martins, Denise Matheus, ... HC-FMUSP Pediatric Post-COVID-19 Study Group
Clinics. 2022;77C:100024
Full text access
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Most often read
Correspondence
Josef Finsterer, Fulvio Alexandre Scorza
10.1016/j.clinsp.2022.100157
This article has been read 2.351 times
View all Most Often read articles
Clinics

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