CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in medical and biomedical sciences.
Edited by: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP)
Journal Information

Last published articles

Original articles
The value of immature granulocyte percentage united with D-Dimer in the evaluation of severe pancreatitis and its prognosis
Tian-Tian Xu, Si-Bing Chen
Highlights

  • The serum levels of IG % and D-D in the study and control group.

  • The serum levels of IG % and D-D in the survival group and death group.

  • Diagnostic value of IG % and D-D in severe pancreatitis.

  • Assessment value of IG % and D-D in prognosis of severe pancreatitis patients.

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Original articles
Effects of different anesthesia methods on labor process and postpartum serum estrogen and progesterone levels in primiparas with painless labor
JunYan Liu, ChongLai Shi, Dan Wang, XiaoDong Cui, LiLi Geng, JingJing Cui, DongMei Sun, Zhuo Yin
Highlights

  • Spinal anesthesia combined with continuous epidural anesthesia has a better anesthesia effect in the painless labor of primiparas.

  • Spinal anesthesia combined with continuous epidural anesthesia can effectually ameliorate the labor process.

  • Spinal anesthesia combined with continuous epidural anesthesia attenuates the expression of serum estrogen and progesterone.

  • Spinal anesthesia combined with continuous epidural anesthesia can be widely employed in clinical practice.

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Original articles
Study on the antidepressant activity of (2R,6R; 2S,6S)-Hydroxynorketamine (HNK) and its derivatives
Dongdong Zang, Xuemei Yang, Hao Wang, Zhenxing Li, Yanjun Ma, Jianxi Liu, Xi Mei, Shupeng Li, ... Zhen Tan
Highlights

  • In the case of 10 mg HNK treatment, compared with saline, the immobile time of compound C and D groups in the glass cylinder area was significantly different.

  • In the locomotor sensitization test, the movement distance of compound C and D groups on day 15 and day 7 mice increased significantly compared with the first day.

  • In the conditioned place preference experiment, compound C and compound D induced conditioned place preference in mice compared with the Veh group.

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Original articles
Food consumption, physical activity and aerobic capacity in systemic lupus erythematosus patients with high cardiovascular risk
Fabiana Infante Smaira, Bruna Caruso Mazzolani, Sofia Mendes Sieczkowska, Marina Romero, Thainá Toledo Ribeiro, Milla Cordeiro Amarante, Sandra Pasoto, Ana Lúcia de Sá Pinto, ... Bruno Gualano
Highlights

  • Patients with systemic lupus erythematosus have decreased functional and aerobic capacity and increased prevalence of cardiovascular diseases.

  • An unhealthy diet, characterized by a high consumption of ultraprocessed foods, as well as physical inactivity increase the cardiovascular risk factor.

  • 58.6% of the patients exhibited high sedentary behavior (above 8h/day) and none of them meet with minimum physical activity recommendation.

  • Our sample reported a slightly higher consumption of ultraprocessed foods than that of the general population (20.0% vs. 18.4% of total energy value).

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Correspondence
Transient, self-limiting, antibody-negative myositis with venetoclax
Carla A. Scorza, Josef Finsterer, Fulvio A. Scorza
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Original articles
Ergonomics appraisals in operating rooms
Jaime Solleiro Rodríguez, Juan Antonio Juanes Méndez, Fernando Blaya Haro
Highlights

  • 100 % of the surgeons surveyed consider that improvements must be made in their work environment.

  • Direct appraisals from surgeons about the main components in an operating room can be a valuable source of information for future developments in the field.

  • Raise visibility in ergonomics, which may improve surgical conditions.

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Original articles
Association of serum 25-hydroxyvitamin D with cardiovascular and all-cause mortality in patients with chronic kidney disease: NHANES 2007‒2018 results
Luohua Li, Jinhan Zhao
Highlights

  • The NHANES data was utilized in this study for conducting a comprehensive long-term follow-up analysis.

  • Deficiency of 25(OH)D was associated with an increased risk of all-cause mortality among patients with CKD.

  • Deficiency of 25(OH)D is associated with an increased risk of cardiovascular mortality in patients with CKD.

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Original articles
Ectopic fat in muscle and poor glycemic control are negatively associated with trabecular bone score in type 2 diabetes
Iana Mizumukai de Araújo, Carlos Ernesto Garrido Salmon, Francisco José Albuquerque de Paula
Highlights

  • Relationship between bone mineral density and trabecular bone score.

  • Body fat percentage has negative relation with trabecular bone score.

  • Reallocation of lipids within muscle has a negative relationship with trabecular bone score.

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Correspondence
NXP-2 positive dermatomyositis with marked dysphagia following an insect bite
Larissa M. Bombardi, Carla Alexandra Scorza, Josef Finsterer, Fulvio Alexandre Scorza
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Clinics

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