Section Index

There is a global increase in childhood myopia and current treatments are limited.

LLRL non-invasive therapy shows promise in myopia control.

LLRL is promising and requires further studies for standardization and safety.

Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental disorder.

Autism spectrum disorder has a significant impact on the patient and their family.

To provide adequate advice is to carry out screening and diagnosis correctly and accurately.

Screening test must be applied, M-CHAT-R/F is recommended.

For diagnosis CARS and ADOS are the most recommended tools.

Impulse Oscillometry (IOS) can be used to analyze lung resistance and reactance in patients with PAH.

Patients with PAH show increased resistance and pulmonary reactance compared to healthy individuals.

The IOS findings showed a good correlation with the spirometric variables.

Photobiomodulation therapy seems to have little or no effect on pain perception during the anesthetic puncture in patients undergoing dental local anesthesia.

Clinical trials found in the literature used different study samples, pain assessment tools, and photobiomodulation therapy protocols.

Further randomized studies should be performed with a standardized methodology to strengthen the current evidence.

The inclusion of dentists in multidisciplinary teams for patients with neurocutaneous syndromes is essential, both on an outpatient and hospital basis.

Interestingly, dentistry can play a relevant role in the early diagnosis and differential diagnosis of patients with neurocutaneous syndromes.

More research in this area is needed.

Obstructive sleep apnea affects one billion people worldwide and is associated with cardiometabolic risk and cognitive impairment.

Drug therapy for the management of sleep apnea has been investigated, but no robust evidence that supports its benefits has been found to date.

The combination of noradrenergic and antimuscarinic drugs shows promising results.

Patients presenting periodontal disease increased the risk of developing gastric adenocarcinoma by 17 %.

The association remained regardless of the diagnostic method for periodontal disease, i.e., clinical examination and self-report.

Moreover, Asian patients with periodontal disease had a higher risk of having gastric adenocarcinoma than American and European patients.

Bisphenola A (BPA) is an endocrine disruptor widely investigated as a possible environmental contributor to the pathogenesis of Polycystic Ovary Syndrome (PCOS).

Due to its structural similarity with the Estrogen molecule (E2), it acts as a xenoestrogen, binding to genomic and non-genomic estrogen receptors, causing metabolic and hormonal changes that lead to PCOS (hyperandrogenism, insulin resistance, hyperinsulinemia, obesity, atherogenic dyslipidemia, anovulation, and ovarian cysts).

The aim and of this review were to present the mechanisms of bisphenol A participation in the pathogenesis of Polycystic Ovary Syndrome.

Epigenetics, hypersensibility and asthma: what do we know so far?

Asthma can be triggered from epigenetic changes.

Early life exposures can contribute to the development and exacerbation of asthma.

DNA methylation profile of certain genes is related to asthma and allergy.

Nasal epithelium samples have shown promise as a tissue for studying DNA methylation changes related to asthma.

To find biomarkers and standardized assays to advance the field of epigenetics in respiratory disorders are still a challenge.

A meta-analysis was applied to analyze the performance of miRNA-29a in diagnosing active pulmonary tuberculosis.

miRNA-29a can be used as a biomarker for the diagnosis of active tuberculosis.

Tuberculosis burden and sample type of miRNA-29a may influence its diagnostic performance.