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Analysis of IgE level influencing factors of common allergens for allergic rhinitis in northeastern China
Yanling Chu, Ai-Hui Yan
Highlights
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The IgE level is lower in female patients with AR compared with male patients.
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AR patients’ IgE Level is affected by allergic history, home-raised plants, and pets.
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IgE levels vary with furniture renewal, asthma, and age in allergic rhinitis patients.
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Clinical significance of TLR7/IL-23/IL-17 signaling pathway in patients with acute respiratory distress syndrome
Lihong Chu, Fengqi Liu, Kankai Tang
Highlights
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TLR7/IL-23/IL-17 pathway activation in ARDS patients implicates immune dysregulation in disease severity.
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TLR7/IL-23/IL-17 pathway is associated with adverse short-term prognosis in ARDS.
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SP-D and CC-16 are positively correlated with TLR7/IL-23/IL-17 pathway activation, indicating lung injury involvement in ARDS progression.
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Analysis of correlation between medial joint line change and lower limb coronal alignment after Oxford unicompartmental knee arthroplasty
Kung-Tseng Hung, Kuo-Yao Hsu, Chieh-Ming Cheng, Yi-Jou Chen, Chih-Hao Chiu, Yi-Shen Chan, Alvin Chao-Yu Chen, Cheng Pang Yang
Highlights
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Postoperative HKAA in Oxford UKA had no correlation with the medial joint line change, the thickness of tibial resection and tibial implant.
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Preoperative HKAA had a strong correlation with postoperative HKAA in Oxford UKA.
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Preoperative smaller LDFA and larger MPTA had a moderate correlation with postoperative HKAA in Oxford UKA.
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Herpesviruses and human papillomaviruses in saliva and biopsies of patients with orofacial tumors
Paa-Kwesi Blankson, Grace E. Parkins, Harriet Naa Afia Blankson, Abiodun Olubayo Fasola, Prince J. Pappoe-Ashong, Matthew O. Boamah, Richard Harry Asmah
Highlights
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Herpesviruses and various HPV genotypes are detectable in tumor samples and saliva of patients with orofacial tumors.
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Prevalent genotypes were EBV (21.3 %), HPV-42 (29 %), HPV-43 (22.7 %), HPV-52 (22.2 %), HPV-39 (18.8 %), and HPV-18 (9.1 %).
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Herpesvirus and HPV DNA were significantly more in the saliva of patients with orofacial tumors than in the control population.
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Epstein Barr virus was more likely to be found in malignant tumor samples than benign orofacial tumors.
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Clinical application of pulse-gated non-enhanced rapid magnetic resonance imaging in the definitive diagnosis of aortic dissection
QinWen Yan, Gang Hu, Qin Wang, Lei Wu, Jun Zhang, Lan He, CiLai Jiao, Si Ma, MinChao Xiong
Highlights
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Free breathing pulse gated non-enhanced rapid MR imaging can obtain images with diagnostic value.
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Multi-plane and multi-angle thin-layer scanning are favorable for the display of the rupture, while some complex tears and bidirectional tears are poorly displayed.
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Free breathing pulse gated non-enhanced rapid MR imaging technique can be used for the exclusive and definitive diagnosis of aortic dissection.
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Non-enhancement peripheral pulse-gating rapid magnetic resonance imaging can be used for deterministic diagnosis of aortic dissection.
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Serum progesterone, glycosylated hemoglobin and insulin levels with the risk of premature rupture of membranes in gestational diabetes mellitus
LiRong Zhou, XueSong Xiong, LianHua Chen
Highlights
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The observation group had higher HbA1c and fasting blood glucose levels. Poor blood glucose control and GWG are risk factors for PROM in GDM patients.
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PROM increases adverse pregnancy outcomes in GDM.
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HbA1c, insulin, and HOMA-IR can predict the risk of PROM in GDM.
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The unexpected silent manifestation of myocardial infarctions in ischemic heart failure patients: Insights from a case-control study
Gabriel Cordeiro Polo Mendes, Paulo Cury Rezende, Arthur Cicupira Rodrigues de Assis, Vitor Coutinho Andrade, Thiago Luis Scudeler, Marcela Francisca da Silva, Mauricio Rigodanzo Mocha, Whady Hueb, ... Roberto Kalil Filho
Highlights
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Silent and Clinically Manifested Myocardial infarctions have similar associated factors.
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Age, sex, hypertension, and diabetes are similarly distributed in both groups.
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Silent myocardial infarction is associated with peripheral diabetic neuropathy.
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Silent myocardial infarction is associated with inferior wall topography.
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Comprehensive exploration of immune checkpoint-related genes in the prognosis and tumor immune microenvironment of pancreatic adenocarcinoma
Xiao Chen, Herui Zhang
Highlights
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Pancreatic Adenocarcinoma (PAAD) exhibits a universally poor prognosis.
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Tumor Immune Microenvironment (TIME) affected the development of tumor.
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Immune Checkpoint-Related Genes (ICRGs) were associated with TIME formation.
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ICRGs were associated with the prognosis of PAAD.
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ICRGs may serve as novel clinical biomarkers and therapeutic targets.
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Custom target-sequencing in triple-negative and luminal breast cancer from young Brazilian patients
Pedro Adolpho de Menezes Pacheco Serio, Daniela Marques Saccaro, Ana Carolina Ribeiro Chaves de Gouvêa, Giselly Encinas, Simone Maistro, Gláucia Fernanda de Lima Pereira, Vinícius Marques Rocha, Larissa Dias de Souza, ... Maria Aparecida Azevedo Koike Folgueira
Highlights
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In breast cancer from young women:
TP53 was affected in 75 % of TN samples, in concomitance with at least one additional driver gene, mainly NF1, NOTCH1 or PTPN13.
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In TN tumors carrying a wild type TP53, other drivers were TSG, like ATR and NF1.
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PIK3CA and GATA3 were the main cancer driver genes in luminal samples, and candidate drivers were GRHL2 and SMURF2.
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CACNA1E is a candidate cancer driver in both luminal and TN samples.
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Effects of N-Acetylcysteine combined with Ambroxol Hydrochloride on clinical symptoms, CRP, and PCT in children with pneumonia
AiLi Xue, Hua Zhang, ShanShan Song, Xia Yu
Highlights
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NAC combined with AH is effective in treating pneumonia.
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NAC combined with AH alleviates clinical symptoms of pneumonia.
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NAC combined with AH reduces inflammatory response in pneumonia.
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NAC combined with AH improves blood gas and immune function in pneumonia.
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NAC combined with AH improves lung function in pneumonia.
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