SousaAM, GrigioTR, AshmawiHA, Ribeiro JúniorU. Cancer pain treatment during the COVID-19 pandemic: institutional recommendations. Clinics (Sao Paulo).. 2020;75:e2208. https://doi.org/10.6061/clinics/2020/e2208
Sousa,Angela Maria; Grigio,Thiago Ramos; Ashmawi,Hazem Adel; Ribeiro Júnior,Ulysses. Cancer pain treatment during the COVID-19 pandemic: institutional recommendations. Clinics (Sao Paulo)., v. 75, e2208, Aug. 2020. https://doi.org/10.6061/clinics/2020/e2208
Sousa,A.M., Grigio,T.R., Ashmawi,H.A., & Ribeiro Júnior,U. (2020). Cancer pain treatment during the COVID-19 pandemic: institutional recommendations. Clinics (Sao Paulo).,75, e2208. https://doi.org/10.6061/clinics/2020/e2208
Sousa,Angela Maria and Grigio,Thiago Ramos and Ashmawi,Hazem Adel and Ribeiro Júnior,Ulysses. Cancer pain treatment during the COVID-19 pandemic: institutional recommendations. Clinics (Sao Paulo). [online]. 2020, vol. 75, [cited 2020-09-04], e2208. Available from: <https://www.clinicsjournal.com/article/cancer-pain-treatment-during-the-covid-19-pandemic-institutional-recommendations/>. ISSN 1807-5932. https://doi.org/10.6061/clinics/2020/e2208
Figure 4
The viability of HUVECs and the HUVEC/monocyte adhesion ability were modified by hypoxia, ketamine, and EX527. (A) Equal amounts of proteins were separated by SDS-PAGE and immunoblotted with antibodies against ICAM-1, E-selectin, and caspase-3. (B) The ratio of the protein expression of each specific protein (ICAM-1, E-selectin, and caspase-3) to the expression of β-actin. (C) Ketamine reversed the hypoxia-mediated decrease of HUVEC viability, while the effect of ketamine was counteracted by EX527. (D) Ketamine reduced the hypoxia-induced increase in monocyte/endothelial cell adhesion, while this effect of ketamine was counteracted by EX527. (*p<0.05 versus the control group, #p<0.05 versus the hypoxia group, & p<0.05 versus the ketamine group, n=5).
, Thiago Ramos Grigio